Investigators
Study information
- Research Area: Malaria
- Research type: prospective community-based single-center reactive case detection (RCD) study
- Start date: Jan 01, 2019
- End date: Apr 30, 2022
Study aim of the objectives
General Objective
To Evaluate the performance (sensitivity, Specificity, positive and negative Predictive value) of an Ultra-sensitive rapid diagnostic test (uRDT) versus conventional RDT (cRDT), compared with microscopy and polymerase chain reaction (PCR) as the gold standards, in reactive case detection to identify malaria infections
Primary Specific objectives
1.To determine the contribution of ultrasensitive RDTs in active detection of asymptomatic patients in Nyagatare and Musanze Districts
2.To identify the contribution of imported malaria cases to malaria burden in Nyagatare and Musanze
Secondary objectives
1.To develop a national malaria diagnostic algorithm from screening to confirmation of malaria
2.To determine the malaria endemicity in the area ( Entomological inoculation rate will be computed as the product of the number of mosquitoes captured by person by night times the ELISA positivity rate)
Study setting/Area (Location)
Nyagatare and Musanze districts
Implementing institution
Rwanda Biomedical Center
Department/Division
MOPD, NRL, BIOS, MRC
Impact on Policy
The finding will inform the guideline and policies for malaria diagnosis