Investigators
Study information
- Research Area: COVID-19
- Research type: Cross-sectional
- Start date: Aug 01, 2021
- End date: Dec 31, 2021
Study aim of the objectives
The main aim of this observational multi-center study is to gain new evidence and improve
knowledge on the prevalence of SARS-CoV-2 infections and SARS-CoV-2 VOCs in the
regions of the participating countries. Specifically, we aim at i) assessing seroprevalence for
SARS-CoV-2 by detecting SARS-CoV-2 specific antibodies among a representative sample
of voluntary blood donors at CHUB, and ii) assessing the existence and spectrum of VOCs
by sequencing of positive SARS-CoV-2 naso-/oropharyngeal swab samples taken during
routine diagnostics at CHUB.
To assure on site quality control, additional serum specimens, which have been obtained
prior to the appearance of COVID-19 will also be assessed for seroprevalence (negative
controls) as well as specimens from laboratory confirmed (RT-PCR) cases of COVID-19,
which are collected at the SARS-CoV-2 test centre at CHUB (positive controls).
Objectives
i. to determine the percentage of individuals (blood donors) with positive SARS-CoV-2
serology (i.e. IgG);
ii. to assess the spectrum of viral variants in the study regions.
Study setting/Area (Location)
CHUB
Implementing institution
CHUB
Department/Division
Research
Impact on Policy
To inform the COVID-19 seroprevalence