Dr. Francois Uwinkindi is the Division Manager of Non-Communicable Diseases Division.
He is a Medical Doctor with a Master’s Degree in Epidemiology from University of Rwanda.
Dr Francois previously served as the Director of the Cancer Diseases Unit for 4 years from 2015 to 2019, the post he occupied after serving for more than five years in national HIV Control Program with different roles and responsibilities in Prevention, Care & Treatment, Monitoring and Evaluation and Clinical Research.
Prior to joining Rwanda Biomedical Centre, he worked as a medical officer at Byumba district hospital for 2 years.
Dr. Gallican is a Head of National HIV, STIs and Hepatitis Programs since December 2020.He is adept at designing, testing and implementation new initiatives to curb HIV infections and transmissions among high-risk group for more than 5years. He holds a Medical Degree in General Medicine and Surgery from National University of Rwanda and Master’s in Epidemiology from Mount Kenya University.
Prior to this position, Dr. Gallican worked with ICAP at Columbia University as the Project Manager for HIV Case-based Surveillance (CBS), seconded to RBC; Before that, He served as a Senior Study Coordinator for the Rwanda Population based HIV impact Assessment Survey (RPHIA) of 2018-2019. Prior to joining ICAP, he worked as General Practitioner within different rural and urban District and referral Hospitals in Rwanda.
He is an active member of different National and Regional technical working groups on HIV and Viral Hepatitis Programs implementations.
Eng. Annick Ishimwe is the current Division Manager for the Medical Technology Division. She has a Bachelor of Engineering in Biomedical Engineering and an MSc in Public Health (Global Health) from the University of Southampton. She is a Chevening Alumni and WEF Global shaper.
Noella Bigirimana is the Deputy Director General at the Rwanda Biomedical Centre, a national health implementation agency in Rwanda.
Noella previously served as Division Manager of Research, Innovation and Data Science at RBC. She has also served as Precision Medicine Fellow at the World Economic Forum, where she focused on co-designing policy and governance approaches to accelerate the adoption of emerging technologies in low-resource settings. Noella has also worked as consultant for WHO and USAID-funded projects in Rwanda and Guinea-Conakry in the post-Ebola period.
Noella currently serves on the Advisory Board of AI Transparency Institute, and also serves as the Advisory Board Chair of the Youth Combating NTDs. She is a World Economic Forum’s Global Shaper in the Kigali Hub, and a contributor at the Future Africa Forum.
She holds a Bachelor’s degree in Human Biology, Health and Society from Cornell University, and a Master’s degree in International Health Policy and Management from the Heller School at Brandeis University.
Dr. Albert TUYISHIME is a Medical Doctor. He holds a master’s degree in clinical Epidemiology from the University of Rwanda.
He serves as the Head of HIV/AIDS, Diseases Prevention and Control Department at Rwanda Biomedical Centre.
For the last 10 years, Dr Albert has worked for Rwanda Biomedical Center, gaining senior-level experience in health programs and systems design, strategic and operational planning, development of Monitoring and Evaluation frameworks for health programs, methods and models for impact and cost analysis as well as development of frameworks and conducive environment for business projects in Health sector.
Dr Albert has also managed the implementation of the Rwanda Health Information Systems (RHIS), including fostering innovation, projects planning, organizing and negotiating the allocation of resources to ensure access to quality health information systems and data.
Prof. Claude Mambo MUVUNYI is the Director General of Rwanda Biomedical Centre. He has more than 10 years of technical, managerial, and strategic experience and expertise in the field of clinical and public laboratory medicine with special focus on clinical microbiology, laboratory systems and service strengthening, and global health security.
Prof. Claude Mambo MUVUNYI is currently a full professor of clinical Microbiology and Laboratory Medicine. He holds a degree in general medicine from the university of Rwanda, a specialization and a PhD in Clinical Microbiology from the University of Ghent, Belgium. He also holds a master’s in medical Virology from the University of Manchester.
Prior to joining the RBC, Prof. Claude Mambo MUVUNYI was a Senior Regional Laboratory Advisor at ICAP at Columbia University, providing technical and strategic leadership support to the Laboratory program/project in building quality assured diagnostic capacities at all levels in the network (public and private health laboratories) of countries in Africa, South and Central Asia, and central America. He has also been a senior consultant for World Health Organization (WHO) supporting WHO’s programs for Antimicrobial Resistance (AMR) surveillance and diagnostic capacity building in African countries. He has been the Head of National reference Laboratory, and the Director of Microbiology unit as well as a study physician for AIDS Vaccine clinical and feasibility research at Project San Francisco.
He has published papers in several international and regional peer-reviewed journals and has made numerous presentations in international conferences. His research interests include evaluation of diagnostic methods (molecular and serological) for infectious diseases and operational research on diagnostic implementation and scale up, and to assess the impact of the new diagnostic for infectious diseases.
Mr Theo Principe UWAYO, ACCA, CPA (R) is the Chief Finance Officer at RBC since 5 February 2022. He joined RBC from 14 April 2021 serving as the Deputy Director General of RBC. Before then, He has had extensive experience in public sector accounting and auditing, whereby he participated actively in audits of Government Budget Agencies and Government Business Enterprises for fifteen years
He studied at Kigali Institute of Science, Technology and Management, currently University of Rwanda- College of Science and Technology where he obtained a Bachelor’s degree (BBA) in Accounting. He completed his ACCA professional accountancy qualification and He is a member in good standing for both Association of Chartered Certified Accountants (ACCA) and Institute of Certified Public Accountants in Rwanda (ICPAR) Rwanda.
Before joining RBC, He worked at the Office of the Auditor General of State Finances where he occupied various posts. He joined RBC while he was working as Director of Audit, whereby his work included overall management of the Department including but not limited to supervision of various audit teams and handling departmental administrative issues as the Head of the Department.
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Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
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Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
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Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
Health Minister, U.S. officials explore new partnerships in global health security – Rwanda Biomedical Centre
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Human growth hormone (HGH) is a naturally occurring peptide produced by the pituitary gland that plays a critical role in regulating body composition, cell repair, and metabolism. It stimulates the liver to produce insulin-like growth factor 1 (IGF-1), which in turn promotes muscle growth, bone density, and overall cellular regeneration. As people age, HGH production declines, leading to decreased muscle mass, increased fat accumulation, reduced energy levels, and a slower recovery from injuries. This decline is often referred to as somatopause, and it can contribute to the aging process both physically and psychologically.
When considering ways to mitigate these effects, two popular approaches are direct HGH supplementation and peptide therapy with growth hormone-releasing peptides such as ipamorelin or sermorelin. Each option has distinct mechanisms, benefits, risks, and practical considerations that influence which may be more appropriate for a given individual.
HGH vs Ipamorelin: Which to Choose?
Mechanism of Action
Direct HGH: Involves the injection of recombinant human growth hormone directly into the bloodstream. The hormone is delivered in a steady or pulsed manner depending on dosing schedule, leading to immediate elevation of circulating HGH levels.
Ipamorelin: A selective ghrelin receptor agonist that stimulates endogenous secretion of HGH from the pituitary gland. By mimicking natural ghrelin signals, ipamorelin promotes cyclic spikes of growth hormone release, closely resembling physiological patterns.
Hormonal Profile and Safety
Direct HGH can produce supraphysiological levels if dosed too high, potentially causing adverse effects such as joint pain, edema, insulin resistance, acromegaly-like changes, and increased cancer risk due to prolonged exposure.
Ipamorelin typically elicits modest increases in HGH that stay within or slightly above normal physiological ranges. Because the body regulates its own hormone production, the risk of overstimulation is lower, leading to fewer side effects such as water retention or glucose intolerance.
Practical Use https://www.valley.md/ipamorelin-vs-sermorelin-which-one-is-for-you Compliance
Direct HGH requires precise dosing (often 1–3 IU per day) and may need to be administered multiple times a week. Some individuals prefer once-daily injections; others opt for higher doses less frequently.
Ipamorelin is often dosed 2–4 times daily, each dose being small (e.g., 200–400 micrograms). The frequent administration can be burdensome but also allows more flexibility in aligning injections with sleep or meals to maximize natural secretion patterns.
Cost Considerations
Direct HGH tends to be expensive due to manufacturing costs and regulatory requirements. Insurance coverage is rare, so out-of-pocket expenses are high.
Ipamorelin is generally cheaper per unit, though cumulative cost can rise with frequent dosing schedules. Additionally, peptide therapy may have fewer regulatory barriers in some regions.
Target Population
Athletes or bodybuilders who seek rapid increases in muscle mass and strength often opt for direct HGH due to its more pronounced anabolic effect.
Individuals focused on anti-aging and metabolic health, such as those concerned about insulin sensitivity, joint function, and longevity, may favor ipamorelin because it mimics natural hormonal rhythms with fewer side effects.
HGH vs Ipamorelin: Which to Choose?
The decision between direct HGH therapy and ipamorelin ultimately hinges on goals, tolerance for risk, lifestyle constraints, and financial resources. If an individual prioritizes maximal anabolic stimulus and can manage potential metabolic disturbances, direct HGH might be the preferred choice. Conversely, if maintaining a more physiological hormone profile with lower side-effect risk is paramount—particularly in older adults or those with insulin resistance—ipamorelin offers a safer alternative that still delivers growth-hormone benefits.
Human Growth Hormone (HGH) Explained
Human growth hormone is a 191-amino-acid peptide that circulates in the blood and exerts its effects through binding to the HGH receptor on target cells. This binding triggers intracellular signaling cascades, notably the Janus kinase–signal transducer and activator of transcription pathway, which ultimately upregulates IGF-1 production. IGF-1 mediates many of the anabolic actions attributed to HGH, such as:
Stimulating protein synthesis in muscle tissue.
Enhancing bone mineral density by promoting osteoblast activity.
Encouraging adipose tissue breakdown (lipolysis) and reducing visceral fat.
Supporting cardiovascular health through improved endothelial function.
The secretion of HGH follows a pulsatile pattern—most intense during deep sleep and after exercise—ensuring that its anabolic effects are synchronized with periods of repair and growth. With age, both the amplitude and frequency of these pulses decline, leading to reduced IGF-1 levels and a cascade of aging symptoms. Hormone replacement therapy seeks to restore these hormonal rhythms, but must balance efficacy against potential risks such as glucose intolerance, edema, carpal tunnel syndrome, and possible promotion of malignant growths.
In summary, understanding the nuances between direct HGH supplementation and peptide therapies like ipamorelin enables individuals to make informed choices that align with their health objectives, risk tolerance, and lifestyle demands.
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